Nepal Journal of Neuroscience
Official Journal of Nepalese Society of Neurosurgeons
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Methanol Poisoning: Our Experience with Recent Outbreak in Nepal.

Reema Rajbhandari, MBBS, Niranjan Acharya, MD, JP Agrawal, MD
Reema Rajbhandari, MBBS Department of Medicine Tribhuvan University Teaching Hospital Kathmandu, Nepal Niranjan Acharya, MD Department of Medicine Tribhuvan University Teaching Hospital Kathmandu, Nepal J P Agrawal MD Department of Medicine Tribhuvan University Teaching Hospital Kathmandu, Nepal

Abstract
Alcoholic drinks adulterated with methanol may result in metabolic acidosis, blindness, and death. Inhibition of alcohol dehydrogenase is the fundamental in the treatment of methanol poisoning. Recently there was an outbreak of methanol poisoning in Sindhupalchowk and Sindhuli in Shrawan, 2065 BS (July- August, 2008 AD). Seven cases presented to Tribhuvan University Teaching Hospital with acute visual impairment and other neurological problems. Active management with high dose intravenous steroid and other accessory modalities was carried out. Vision of only 2 cases improved and othersí didnít. Other helpful modes of treatment are fomepizole, folate, hemodialysis etc. Health workers and general public should be well educated about health hazard of local alcoholic drinks to prevent methanol poisoning. Strict legal forces with proper rules and regulation should be implemented. By this, many lives and vision of victims can be saved.

Key Words: folate, fomepizole, hemodialysis, methanol